Cargando…

Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer

SETDB2 is a histone H3 lysine 9 (H3K9) tri-methyltransferase that is involved in transcriptional gene silencing. Since it is still unknown whether SETDB2 is linked to carcinogenesis, we studied alterations and functions of SETDB2 in human gastric cancers (GCs). SETDB2 protein was highly expressed in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishikawaji, Taketo, Akiyama, Yoshimitsu, Shimada, Shu, Kojima, Kazuyuki, Kawano, Tatsuyuki, Eishi, Yoshinobu, Yuasa, Yasuhito, Tanaka, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341872/ https://www.ncbi.nlm.nih.gov/pubmed/27572307 http://dx.doi.org/10.18632/oncotarget.11625

Ejemplares similares

Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression
por: Akiyama, Yoshimitsu, et al.
Publicado: (2015)

Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML
por: Mu, Guangfu, et al.
Publicado: (2020)

A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors
por: Fukamachi, Hiroshi, et al.
Publicado: (2019)

The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma
por: Ceol, Craig J., et al.
Publicado: (2011)

DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells
por: Sakamoto, Ayuna, et al.
Publicado: (2015)

Role of histone methyltransferase SETDB1 in regulation of tumourigenesis and immune response
por: Zhao, Zhipeng, et al.
Publicado: (2022)

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
por: Rodriguez-Paredes, M, et al.
Publicado: (2014)

A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing
por: Kato, Masaki, et al.
Publicado: (2018)

Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models
por: Shimada, Shu, et al.
Publicado: (2018)

ZNF274 Recruits the Histone Methyltransferase SETDB1 to the 3′ Ends of ZNF Genes
por: Frietze, Seth, et al.
Publicado: (2010)

Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion
por: Sun, Yi, et al.
Publicado: (2014)

55270 The Histone Methyltransferase SETDB2 Regulates Inflammation in Normal and Diabetic Wound Repair
por: denDekker, Aaron, et al.
Publicado: (2021)

The cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for embryonic stem cells
por: Rapone, Roberta, et al.
Publicado: (2023)

Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53
por: Chen, Keli, et al.
Publicado: (2017)

Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer
por: Hashimoto, Yutaka, et al.
Publicado: (2013)

MicroRNA-126 Inhibits SOX2 Expression and Contributes to Gastric Carcinogenesis
por: Otsubo, Takeshi, et al.
Publicado: (2011)

Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
por: Fei, Qi, et al.
Publicado: (2015)

The Histone Methyltransferase SETDB1 Modulates Survival of Spermatogonial Stem/Progenitor Cells Through NADPH Oxidase
por: Li, Xueliang, et al.
Publicado: (2020)

Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis
por: Zhang, Xinbo, et al.
Publicado: (2021)

Structure, Activity and Function of the SETDB1 Protein Methyltransferase
por: Markouli, Mariam, et al.
Publicado: (2021)

Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype
por: Daxinger, Lucia, et al.
Publicado: (2016)

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
por: Timms, Richard T., et al.
Publicado: (2016)

Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma
por: Zhang, Yuqin, et al.
Publicado: (2018)

Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer
por: Ishii, Takeshi, et al.
Publicado: (2022)

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection
por: Schliehe, Christopher, et al.
Publicado: (2014)

Histone lysine methyltransferase SETDB2 suppresses NRF2 to restrict tumor progression and modulates chemotherapy sensitivity in lung adenocarcinoma
por: Yuan, Guangda, et al.
Publicado: (2022)

Expression of the Major and Pro-Oncogenic H3K9 Lysine Methyltransferase SETDB1 in Non-Small Cell Lung Cancer
por: Cruz-Tapias, Paola, et al.
Publicado: (2019)

Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity
por: Ishimoto, Kenji, et al.
Publicado: (2016)

Different clinical significance of FGFR1–4 expression between diffuse-type and intestinal-type gastric cancer
por: Inokuchi, Mikito, et al.
Publicado: (2017)

Frequent Microsatellite Instabilities and Analyses of the Related Genes in Familial Gastric Cancers
por: Akiyama, Yoshimitsu, et al.
Publicado: (1996)

The Updating of Biological Functions of Methyltransferase SETDB1 and Its Relevance in Lung Cancer and Mesothelioma
por: Yuan, Li, et al.
Publicado: (2021)

Akt methylation by SETDB1 promotes Akt kinase activity and oncogenic functions
por: Guo, Jianping, et al.
Publicado: (2019)

Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer
por: Almeida-Rios, Diogo, et al.
Publicado: (2016)

Histone Methyltransferases Useful in Gastric Cancer Research
por: Reyes, Dafne Alejandra, et al.
Publicado: (2021)

The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages
por: Hachiya, Rumi, et al.
Publicado: (2016)

CD49f(high) Cells Retain Sphere-Forming and Tumor-Initiating Activities in Human Gastric Tumors
por: Fukamachi, Hiroshi, et al.
Publicado: (2013)

Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells
por: Watanabe, Hideo, et al.
Publicado: (2008)

Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer
por: Zhao, Li-hao, et al.
Publicado: (2021)

The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells
por: Smolko, Anne E., et al.
Publicado: (2018)

Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
por: Robbez-Masson, Luisa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_87bvpu3h3mudlq38ssb8vdbeuo