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Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response
Tuberculosis, caused by Mycobacterium tuberculosis (MTB) infection, remains a grave global public health burden which claims the lives around two to three million annually. PE and PPE proteins, featured by the Pro-Glu (PE) or Pro-Pro-Glu (PPE) motifs at the conserved N-terminal domain, are abundant...
Autores principales: | Deng, Wanyan, Yang, Wenmin, Zeng, Jie, Abdalla, Abualgasim Elgaili, Xie, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341880/ https://www.ncbi.nlm.nih.gov/pubmed/27634911 http://dx.doi.org/10.18632/oncotarget.12030 |
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