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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status
PROX1 is a transcription factor with an essential role in embryonic development and determination of cell fate. In addition, PROX1 has been ascribed suppressive as well as oncogenic roles in several human cancers, including brain tumors. In this study we explored the correlation between PROX1 expres...
Autores principales: | Roodakker, Kenney R., Elsir, Tamador, Edqvist, Per-Henrik D., Hägerstrand, Daniel, Carlson, Joseph, Lysiak, Malgorzata, Henriksson, Roger, Pontén, Fredrik, Rosell, Johan, Söderkvist, Peter, Stupp, Roger, Tchougounova, Elena, Nistér, Monica, Malmström, Annika, Smits, Anja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341919/ https://www.ncbi.nlm.nih.gov/pubmed/27626492 http://dx.doi.org/10.18632/oncotarget.11957 |
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