Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening

The Androgen Receptor (AR) plays a key role in prostate biology and in the progression of prostate cancer (PCa) to castration resistance. The role of microRNAs (miRNAs) in aberrant AR signaling have not been fully characterized. Here we screened a library of 810 miRNA mimics to identify miRNAs that...

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Detalles Bibliográficos
Autores principales: Kumar, Binod, Khaleghzadegan, Salar, Mears, Brian, Hatano, Koji, Kudrolli, Tarana A., Chowdhury, Wasim H., Yeater, David B., Ewing, Charles M., Luo, Jun, Isaacs, William B., Marchionni, Luigi, Lupold, Shawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341930/
https://www.ncbi.nlm.nih.gov/pubmed/27683042
http://dx.doi.org/10.18632/oncotarget.12241

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