PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma

Programmed Death-1 (PD-1), an inhibitory receptor expressed by activated lymphocytes, is involved in regulating T- and B-cell responses. PD-1 and its ligands are exploited by a variety of cancers to facilitate tumor escape through PD-1-mediated functional exhaustion of effector T cells. Here, we rep...

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Detalles Bibliográficos
Autores principales: Beldi-Ferchiou, Asma, Lambert, Marion, Dogniaux, Stéphanie, Vély, Frédéric, Vivier, Eric, Olive, Daniel, Dupuy, Stéphanie, Levasseur, Frank, Zucman, David, Lebbé, Céleste, Sène, Damien, Hivroz, Claire, Caillat-Zucman, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341956/
https://www.ncbi.nlm.nih.gov/pubmed/27662664
http://dx.doi.org/10.18632/oncotarget.12150

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