Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia

Cancer initiating cells (CICs) represent a subpopulation of cancer cells, which are responsible for tumor growth and resistance to chemotherapy. Herein, we first used a cell-based aldehyde dehydrogenase (ALDH) activity assay to identify that YMGKI-2 (also named as Ergone), an active component purifi...

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Detalles Bibliográficos
Autores principales: Chang, Ching-Wen, Chen, Yu-Syuan, Chen, Chien-Chih, Chan, Ik-On, Chen, Chin-Chu, Sheu, Sen-Je, Lin, Ting-wei, Chou, Shiu-Huey, Liu, Chung-Ji, Lee, Te-Chang, Lo, Jeng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341960/
https://www.ncbi.nlm.nih.gov/pubmed/27682875
http://dx.doi.org/10.18632/oncotarget.12194

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