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Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis

Patients with mucoepidermoid carcinoma (MEC) experience low survival rates and high morbidity following treatment, yet the intrinsic resistance of MEC cells to ionizing radiation (IR) and the mechanisms underlying acquired resistance remain unexplored. Herein, we demonstrated that low doses of IR in...

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Detalles Bibliográficos
Autores principales: Wagner, Vivian P., Martins, Marco A.T., Martins, Manoela D., Warner, Kristy A., Webber, Liana P., Squarize, Cristiane H., Nör, Jacques E., Castilho, Rogerio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341961/
https://www.ncbi.nlm.nih.gov/pubmed/27682876
http://dx.doi.org/10.18632/oncotarget.12195

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