A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment

Metastasis currently remains the predominant cause of breast carcinoma treatment failure. The effective targeting of metastasis-related-pathways in cancer holds promise for a new generation of therapeutics. In this study, we developed an novel Asp-UA conjugate, which was composed of classical “old d...

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Detalles Bibliográficos
Autores principales: Tang, Qiao, Liu, Yajun, Li, Tao, Yang, Xiang, Zheng, Guirong, Chen, Hongning, Jia, Lee, Shao, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341967/
https://www.ncbi.nlm.nih.gov/pubmed/27683033
http://dx.doi.org/10.18632/oncotarget.12232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341967/
https://www.ncbi.nlm.nih.gov/pubmed/27683033
http://dx.doi.org/10.18632/oncotarget.12232

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