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Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response

Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress. Co-culture experiments showed that adipocytes protect ALL c...

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Detalles Bibliográficos
Autores principales: Sheng, Xia, Tucci, Jonathan, Parmentier, Jean-Hugues, Ji, Lingyun, Behan, James W., Heisterkamp, Nora, Mittelman, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341969/
https://www.ncbi.nlm.nih.gov/pubmed/27705905
http://dx.doi.org/10.18632/oncotarget.12246