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Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response
Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress. Co-culture experiments showed that adipocytes protect ALL c...
Autores principales: | Sheng, Xia, Tucci, Jonathan, Parmentier, Jean-Hugues, Ji, Lingyun, Behan, James W., Heisterkamp, Nora, Mittelman, Steven D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341969/ https://www.ncbi.nlm.nih.gov/pubmed/27705905 http://dx.doi.org/10.18632/oncotarget.12246 |
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