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MiR-128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway
Gefitinib is a first line anti-tumor drug used for the treatment of patients with non-small cell lung cancer (NSCLC) harboring EGFR mutations. However, the drug resistance to gefitinib limits its clinical application. Here, we observed the CSCs of PC9 are obviously resistant to gefitinib compared wi...
Autores principales: | Jiang, Jingjin, Feng, Xiaoning, Zhou, Wenjing, Wu, Yue, Yang, Yunmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341972/ https://www.ncbi.nlm.nih.gov/pubmed/27690301 http://dx.doi.org/10.18632/oncotarget.12283 |
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