Cargando…

Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

BACKROUND: Steatohepatitis (SH)-associated liver carcinogenesis is an increasingly important issue in clinical medicine. SH is morphologically characterized by steatosis, hepatocyte injury, ballooning, hepatocytic cytoplasmic inclusions termed Mallory-Denk bodies (MDBs), inflammation and fibrosis. R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bettermann, Kira, Mehta, Anita Kuldeep, Hofer, Eva M., Wohlrab, Christina, Golob-Schwarzl, Nicole, Svendova, Vendula, Schimek, Michael G., Stumptner, Cornelia, Thüringer, Andrea, Speicher, Michael R., Lackner, Carolin, Zatloukal, Kurt, Denk, Helmut, Haybaeck, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341981/ https://www.ncbi.nlm.nih.gov/pubmed/27689336 http://dx.doi.org/10.18632/oncotarget.12325

Ejemplares similares

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype()()
por: Golob-Schwarzl, Nicole, et al.
Publicado: (2018)

Steatosis and Steatohepatitis: Complex Disorders
por: Bettermann, Kira, et al.
Publicado: (2014)

Corrigendum to High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype12 [Translational Oncology Volume 12, Issue 2, February 2019, Pages 256-268]
por: Golob-Schwarzl, N., et al.
Publicado: (2020)

Intermediate filament cytoskeleton of the liver in health and disease
por: Strnad, P., et al.
Publicado: (2008)

MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis
por: de Conti, Aline, et al.
Publicado: (2017)

Priming, Triggering, Adaptation and Senescence (PTAS): A Hypothesis for a Common Damage Mechanism of Steatohepatitis
por: Abuja, Peter M., et al.
Publicado: (2021)

Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis
por: Kawamura, Satoshi, et al.
Publicado: (2022)

Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies
por: Zatloukal, Bernhard, et al.
Publicado: (2014)

Liver Fibrogenesis in Non-Alcoholic Steatohepatitis
por: Bian, Zhaolian, et al.
Publicado: (2012)

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice
por: Miyazaki, Tsuneyuki, et al.
Publicado: (2016)

Gene Expression and DNA Methylation Alterations During Non-alcoholic Steatohepatitis-Associated Liver Carcinogenesis
por: Dreval, Kostiantyn, et al.
Publicado: (2019)

Gene Expression Profiling Unravels Cancer-Related Hepatic Molecular Signatures in Steatohepatitis but Not in Steatosis
por: Starmann, Julia, et al.
Publicado: (2012)

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer
por: Bysani, Madhusudhan, et al.
Publicado: (2013)

Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains
por: Pandey, Vikash, et al.
Publicado: (2014)

Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis
por: Dongiovanni, Paola, et al.
Publicado: (2015)

Murine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis
por: Ninomiya, Masashi, et al.
Publicado: (2012)

The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis
por: Méndez-Sánchez, Nahum, et al.
Publicado: (2020)

Harnessing Muscle–Liver Crosstalk to Treat Nonalcoholic Steatohepatitis
por: Chakravarthy, Manu V., et al.
Publicado: (2020)

Nonalcoholic steatohepatitis and hepatocellular carcinoma: Beyond the boundaries of the liver
por: Gupta, Tarana
Publicado: (2022)

Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers
por: Liu, Xiao, et al.
Publicado: (2023)

Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes
por: Ishizu-Higashi, Shoko, et al.
Publicado: (2014)

Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
por: Imajo, Kento, et al.
Publicado: (2013)

Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
por: Uchida, Shizuka, et al.
Publicado: (2020)

Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis
por: Li, Haiou, et al.
Publicado: (2020)

Characterization of Gut Microbiome in Liver Transplant Recipients With Nonalcoholic Steatohepatitis
por: Satapathy, Sanjaya K., et al.
Publicado: (2020)

Emerging Roles of Liver Sinusoidal Endothelial Cells in Nonalcoholic Steatohepatitis
por: Furuta, Kunimaro, et al.
Publicado: (2020)

A 3D Human Liver Model of Nonalcoholic Steatohepatitis
por: Duriez, Marion, et al.
Publicado: (2020)

Nonalcoholic Steatohepatitis Disrupts Diurnal Liver Transcriptome Rhythms in Mice
por: de Assis, Leonardo Vinicius Monteiro, et al.
Publicado: (2023)

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis
por: Raselli, Tina, et al.
Publicado: (2019)

Circulating Citrate Is Associated with Liver Fibrosis in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
por: Amjad, Waseem, et al.
Publicado: (2023)

Outcomes of liver transplantation for non-alcoholic steatohepatitis: A European Liver Transplant Registry study
por: Haldar, Debashis, et al.
Publicado: (2019)

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates
por: Magin, Thomas M., et al.
Publicado: (1998)

Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis
por: Spahr, Laurent, et al.
Publicado: (2011)

S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis
por: Mazo, Daniel FC, et al.
Publicado: (2013)

Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats
por: Yang, Ze-ran, et al.
Publicado: (2016)

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis
por: Matsunaga, Yasuka, et al.
Publicado: (2015)

Pathogenesis of Nonalcoholic Steatohepatitis: Interactions between Liver Parenchymal and Nonparenchymal Cells
por: Magee, Nancy, et al.
Publicado: (2016)

Lamin Deficiency in the Liver Sets the Stage for Nonalcoholic Steatohepatitis Development in Males
por: Hendrikx, Tim, et al.
Publicado: (2017)

Serological biomarkers associate ultrasound characteristics of steatohepatitis in mice with liver cancer
por: Cui, Guozhen, et al.
Publicado: (2018)

The role of hepatic macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
por: Cha, Ji-Young, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vf5qe2ps9qgv88phmdadoqubp1