Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases

The detailed molecular mechanisms and safety issues of recombinant human bone morphogenetic protein-2 (rhBMP-2) usage in bone graft substitution remain poorly understood. To investigate the molecular mechanisms underlying the function of rhBMP-2 in gastric cancer cells, we used microarrays to determ...

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Detalles Bibliográficos
Autores principales: Lee, Kwang Bok, Jin, Hua, Ye, Shuai, Park, Byung Hyun, Kim, Soo Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341992/
https://www.ncbi.nlm.nih.gov/pubmed/27636990
http://dx.doi.org/10.18632/oncotarget.11969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341992/
https://www.ncbi.nlm.nih.gov/pubmed/27636990
http://dx.doi.org/10.18632/oncotarget.11969

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