Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells

Effective new therapies are urgently needed for the treatment of multiple myeloma (MM), an incurable hematological malignancy. In this study, we evaluated the effects of piperlongumine on MM cell proliferation both in vivo and in vitro. Piperlongumine inhibited the proliferation of MM cells by induc...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Sun, Yueyue, Shi, Min, Xia, Dandan, Zhao, Kai, Zeng, Lingyu, Yao, Ruosi, Zhang, Ying, Li, Zhenyu, Niu, Mingshan, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341994/
https://www.ncbi.nlm.nih.gov/pubmed/27634873
http://dx.doi.org/10.18632/oncotarget.11988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341994/
https://www.ncbi.nlm.nih.gov/pubmed/27634873
http://dx.doi.org/10.18632/oncotarget.11988

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