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Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells
Effective new therapies are urgently needed for the treatment of multiple myeloma (MM), an incurable hematological malignancy. In this study, we evaluated the effects of piperlongumine on MM cell proliferation both in vivo and in vitro. Piperlongumine inhibited the proliferation of MM cells by induc...
Autores principales: | Yao, Yao, Sun, Yueyue, Shi, Min, Xia, Dandan, Zhao, Kai, Zeng, Lingyu, Yao, Ruosi, Zhang, Ying, Li, Zhenyu, Niu, Mingshan, Xu, Kailin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341994/ https://www.ncbi.nlm.nih.gov/pubmed/27634873 http://dx.doi.org/10.18632/oncotarget.11988 |
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