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Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging
Mounting evidence suggests that the urokinase plasminogen activator (uPA) and its receptor (uPAR) play a central role in tumor progression. The goal of this study was to develop an (89)Zr-labeled, antibody-based positron emission tomography (PET) tracer for quantitative imaging of the uPA/uPAR syste...
Autores principales: | Yang, Dongzhi, Severin, Gregory W., Dougherty, Casey A., Lombardi, Rachel, Chen, Daiqin, Van Dort, Marcian E., Barnhart, Todd E., Ross, Brian D., Mazar, Andrew P., Hong, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342023/ https://www.ncbi.nlm.nih.gov/pubmed/27729618 http://dx.doi.org/10.18632/oncotarget.12528 |
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