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Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging

Mounting evidence suggests that the urokinase plasminogen activator (uPA) and its receptor (uPAR) play a central role in tumor progression. The goal of this study was to develop an (89)Zr-labeled, antibody-based positron emission tomography (PET) tracer for quantitative imaging of the uPA/uPAR syste...

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Detalles Bibliográficos
Autores principales: Yang, Dongzhi, Severin, Gregory W., Dougherty, Casey A., Lombardi, Rachel, Chen, Daiqin, Van Dort, Marcian E., Barnhart, Todd E., Ross, Brian D., Mazar, Andrew P., Hong, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342023/
https://www.ncbi.nlm.nih.gov/pubmed/27729618
http://dx.doi.org/10.18632/oncotarget.12528

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