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Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer
Radiotherapy is used to treat many different human tumors. Paradoxically, radiation can activate TGF-β1 signaling and induce the epithelial-mesenchymal transition (EMT), which is associated with enhanced tumor progression. This study investigated the inhibitory effects of halofuginone, a plant-deriv...
Autores principales: | Chen, Yang, Liu, Weishuai, Wang, Peng, Hou, Hailing, Liu, Ningbo, Gong, Linlin, Wang, Youyou, Ji, Kai, Zhao, Lujun, Wang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342082/ https://www.ncbi.nlm.nih.gov/pubmed/27533085 http://dx.doi.org/10.18632/oncotarget.11217 |
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