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Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation
Cancer stem cells (CSCs) are responsible for tumor initiation and progression. We previously showed that Delta-like homolog 1 (DLK1) may be a therapeutic target against the CSCs of human hepatocellular carcinoma (HCC). However, the therapeutic efficacy and underlying mechanism remain unclear. Here w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342093/ https://www.ncbi.nlm.nih.gov/pubmed/27683116 http://dx.doi.org/10.18632/oncotarget.12214 |