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Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation

Cancer stem cells (CSCs) are responsible for tumor initiation and progression. We previously showed that Delta-like homolog 1 (DLK1) may be a therapeutic target against the CSCs of human hepatocellular carcinoma (HCC). However, the therapeutic efficacy and underlying mechanism remain unclear. Here w...

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Detalles Bibliográficos
Autores principales: Cai, Chun-Miao, Xiao, Xu, Wu, Bing-Hao, Wei, Bao-Feng, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342093/
https://www.ncbi.nlm.nih.gov/pubmed/27683116
http://dx.doi.org/10.18632/oncotarget.12214

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