Cargando…

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Donghui, Jia, Zhifang, You, Lili, Wu, Yanhua, Hou, Zhen, Suo, Yueer, Zhang, Houjun, Wen, Simin, Tsukamoto, Tetsuya, Oshima, Masanobu, Jiang, Jing, Cao, Xueyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342136/ https://www.ncbi.nlm.nih.gov/pubmed/27713126 http://dx.doi.org/10.18632/oncotarget.12443

Ejemplares similares

The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils
por: Cao, Donghui, et al.
Publicado: (2016)

Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis
por: Wu, Yanhua, et al.
Publicado: (2017)

Canolol Inhibits Gastric Tumors Initiation and Progression through COX-2/PGE2 Pathway in K19-C2mE Transgenic Mice
por: Cao, Donghui, et al.
Publicado: (2015)

Polymorphism of DNA Methyltransferase 3b and Association with Development and Prognosis in Gastric Cancer
por: Wang, Chuan, et al.
Publicado: (2015)

Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy
por: Jia, Zhifang, et al.
Publicado: (2016)

Polymorphisms of the DNA Methyltransferase 1 Associated with Reduced Risks of Helicobacter pylori Infection and Increased Risks of Gastric Atrophy
por: Jiang, Jing, et al.
Publicado: (2012)

PD-1 and PD-L1 co-expression predicts favorable prognosis in gastric cancer
por: Wu, Yanhua, et al.
Publicado: (2017)

Long non-coding RNA polymorphisms on 8q24 are associated with the prognosis of gastric cancer in a Chinese population
por: Zhang, Yangyu, et al.
Publicado: (2020)

Positive H. pylori status predicts better prognosis of non-cardiac gastric cancer patients: results from cohort study and meta-analysis
por: Jia, Zhifang, et al.
Publicado: (2022)

Genetic estimation of correlations and causalities between multifaceted modifiable factors and gastro-oesophageal reflux disease
por: Sun, Yuanlin, et al.
Publicado: (2022)

18β-glycyrrhetinic acid inhibits rotavirus replication in culture
por: Hardy, Michele E, et al.
Publicado: (2012)

Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid
por: Cai, Dong, et al.
Publicado: (2020)

Long Noncoding RNA HOXB-AS1 Is Upregulated in Endometrial Carcinoma and Sponged miR-149-3p to Upregulate Wnt10b
por: Liu, Da, et al.
Publicado: (2020)

Microsatellite instability and Epstein-Barr virus combined with PD-L1 could serve as a potential strategy for predicting the prognosis and efficacy of postoperative chemotherapy in gastric cancer
por: Yang, Na, et al.
Publicado: (2021)

Dietary inflammatory index, and depression and mortality risk associations in U.S. adults, with a special focus on cancer survivors
por: Zhang, Yuzheng, et al.
Publicado: (2022)

Specific Binding and Characteristics of 18β-Glycyrrhetinic Acid in Rat Brain
por: Mizoguchi, Kazushige, et al.
Publicado: (2014)

The versatility of 18ß-glycyrrhetinic acid in attenuating pulmonary inflammatory disorders
por: Mohamad, Mohamad Siddiq Bin, et al.
Publicado: (2023)

Differential Induction of Isolated Lymphoid Follicles in the Gut by 18β-Glycyrrhetinic Acid
por: Hendricks, Jay M., et al.
Publicado: (2014)

Antibacterial activity of 18β-glycyrrhetinic acid against Neisseria gonorrhoeae in vitro
por: Zhao, Yuanyuan, et al.
Publicado: (2023)

18β-glycyrrhetinic Acid Modulated Autophagy is Cytotoxic to Breast Cancer Cells
por: Hsu, Yu-Chih, et al.
Publicado: (2023)

Anti-Photoaging Effects of Nanocomposites of Amphiphilic Chitosan/18β-Glycyrrhetinic Acid
por: Quan, Weiyan, et al.
Publicado: (2023)

Synthesis and Antiviral and Antitumor Activities of Novel 18β-Glycyrrhetinic Acid Derivatives
por: Pan, Bo-Wen, et al.
Publicado: (2023)

Decreased Galectin-9 and Increased Tim-3 Expression Are Related to Poor Prognosis in Gastric Cancer
por: Jiang, Jing, et al.
Publicado: (2013)

A Review of the Antiviral Activities of Glycyrrhizic Acid, Glycyrrhetinic Acid and Glycyrrhetinic Acid Monoglucuronide
por: Zuo, Jiawei, et al.
Publicado: (2023)

Decay chain $^{149}_{64}$Gd --> $^{149}_{63}$Eu --> $^{149}_{62}$Sm
por: Cabrera, J A, et al.
Publicado: (1991)

Preparation and Antibacterial Activity Evaluation of 18-β-glycyrrhetinic Acid Loaded PLGA Nanoparticles
por: Darvishi, Behrad, et al.
Publicado: (2015)

Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid
por: Passali, Desiderio, et al.
Publicado: (2017)

Effects of 18β-Glycyrrhetinic Acid on Fungal Protease-Induced Airway Inflammatory Responses
por: Kim, Yun Hee, et al.
Publicado: (2018)

Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats
por: Yang, Guanghua, et al.
Publicado: (2017)

Pharmacological Features of 18β-Glycyrrhetinic Acid: A Pentacyclic Triterpenoid of Therapeutic Potential
por: Shinu, Pottathil, et al.
Publicado: (2023)

Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus
por: Oyama, Kentaro, et al.
Publicado: (2016)

Study of $^{149}_{64}$Gd --> $^{149}_{63}$Eu --> $^{149}_{62}$Sm decay chain
por: Cabrera, J A, et al.
Publicado: (1992)

miR‑149‑3p suppresses the proliferation and metastasis of glioma cells by targeting the CBX2/Wnt/β‑catenin pathway
por: Wang, Yanjun, et al.
Publicado: (2023)

miR-149 in Human Cancer: A Systemic Review
por: He, Yunjie, et al.
Publicado: (2018)

miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1
por: Ke, Yang, et al.
Publicado: (2013)

Prevention of D-GalN/LPS-induced ALI by 18β-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
por: Wu, Shouyan, et al.
Publicado: (2021)

In Silico and In Vivo Anti-Malarial Studies of 18β Glycyrrhetinic Acid from Glycyrrhiza glabra
por: Kalani, Komal, et al.
Publicado: (2013)

Charge-transfer interaction mediated organogels from 18β-glycyrrhetinic acid appended pyrene
por: Hu, Jun, et al.
Publicado: (2013)

Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats
por: Zhang, Min, et al.
Publicado: (2019)

18-α-glycyrrhetinic acid alleviates oxidative damage in periodontal tissue by modulating the interaction of Cx43 and JNK/NF-κB pathways
por: Cao, Niuben, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1gof773nffmie9lbvjatqokhuj