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18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and...

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Detalles Bibliográficos
Autores principales: Cao, Donghui, Jia, Zhifang, You, Lili, Wu, Yanhua, Hou, Zhen, Suo, Yueer, Zhang, Houjun, Wen, Simin, Tsukamoto, Tetsuya, Oshima, Masanobu, Jiang, Jing, Cao, Xueyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342136/
https://www.ncbi.nlm.nih.gov/pubmed/27713126
http://dx.doi.org/10.18632/oncotarget.12443

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