Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells

Intracellular vimentin overexpression has been associated with epithelial–mesenchymal transition, metastasis, invasion, and proliferation, but cell surface vimentin (CSV) is less understood. Furthermore, it remains unknown whether CSV can serve as a therapeutic target in CSV-expressing tumor cells....

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Detalles Bibliográficos
Autores principales: Noh, Hyangsoon, Yan, Jun, Hong, Sungguan, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Xia, Xueqing, Heimberger, Amy B., Li, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342141/
https://www.ncbi.nlm.nih.gov/pubmed/27713131
http://dx.doi.org/10.18632/oncotarget.12458

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