A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors

Epidermal Growth Factor Receptor (EGFR) activates a robust signalling network to which colon cancer tumours often become addicted. Cetuximab, one of the monoclonal antibodies targeting this pathway, is employed to treat patients with colorectal cancer. However, many patients are intrinsically refrac...

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Detalles Bibliográficos
Autores principales: Gelfo, Valerio, Rodia, Maria Teresa, Pucci, Michela, Dall'Ora, Massimiliano, Santi, Spartaco, Solmi, Rossella, Roth, Lee, Lindzen, Moshit, Bonafè, Massimiliano, Bertotti, Andrea, Caramelli, Elisabetta, Lollini, Pier-Luigi, Trusolino, Livio, Yarden, Yosef, D'Uva, Gabriele, Lauriola, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342152/
https://www.ncbi.nlm.nih.gov/pubmed/27708224
http://dx.doi.org/10.18632/oncotarget.12354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342152/
https://www.ncbi.nlm.nih.gov/pubmed/27708224
http://dx.doi.org/10.18632/oncotarget.12354

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