Cargando…
Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo
Among human RNA viruses, hepatitis C virus (HCV) is unusual in that it causes persistent infection in the majority of infected people. To establish persistence, HCV evades host innate and adaptive immune responses by multiple mechanisms. Recent studies identified virus genome-derived small RNAs (vsR...
Autores principales: | Bhattarai, Nirjal, McLinden, James H., Xiang, Jinhua, Mathahs, M. Meleah, Schmidt, Warren N., Kaufman, Thomas M., Stapleton, Jack T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342304/ https://www.ncbi.nlm.nih.gov/pubmed/28235043 http://dx.doi.org/10.1371/journal.ppat.1006232 |
Ejemplares similares
-
Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation
por: Bhattarai, Nirjal, et al.
Publicado: (2015) -
Src-family kinases negatively regulate NFAT signaling in resting human T cells
por: Baer, Alan, et al.
Publicado: (2017) -
Heme and HO-1 Inhibition of HCV, HBV, and HIV
por: Schmidt, Warren N., et al.
Publicado: (2012) -
TCR-independent Activation in Presence of a Src-family Kinase Inhibitor Improves CAR-T Cell Product Attributes
por: Lamture, Gauri, et al.
Publicado: (2022) -
HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes
por: Zhu, Zhaowen, et al.
Publicado: (2017)