Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Renal fibrosis cannot be adequately treated since anti-fibrotic treatment is lacking. Interferon-γ is a pro-inflammatory cytokine with anti-fibrotic properties. Clinical use of interferon-γ is hampered due to inflammation-mediated systemic side effects. We used an interferon-γ peptidomimetic (mimγ)...

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Detalles Bibliográficos
Autores principales: Poosti, Fariba, Bansal, Ruchi, Yazdani, Saleh, Prakash, Jai, Beljaars, Leonie, van den Born, Jacob, de Borst, Martin H., van Goor, Harry, Hillebrands, Jan-Luuk, Poelstra, Klaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342338/
https://www.ncbi.nlm.nih.gov/pubmed/27509062
http://dx.doi.org/10.18632/oncotarget.11095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342338/
https://www.ncbi.nlm.nih.gov/pubmed/27509062
http://dx.doi.org/10.18632/oncotarget.11095

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