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Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma

Recurrent somatic mutations in the promoter region of telomerase reverse transcriptase (TERT) gene and in the exon 3 of CTNNB1 gene have been recognized as common events in hepatocellular carcinoma (HCC) with variable frequencies depending on etiology and geographical region. We have analyzed TERT p...

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Detalles Bibliográficos
Autores principales: Pezzuto, Francesca, Izzo, Francesco, Buonaguro, Luigi, Annunziata, Clorinda, Tatangelo, Fabiana, Botti, Gerardo, Buonaguro, Franco M., Tornesello, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342339/
https://www.ncbi.nlm.nih.gov/pubmed/27276713
http://dx.doi.org/10.18632/oncotarget.9801