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HDAC6 inhibition prevents TNF-α-induced caspase 3 activation in lung endothelial cell and maintains cell-cell junctions

Pro-inflammatory mediators such as TNF-α induce caspase activation in endothelial cells, which leads to degradation of cellular proteins, induction of apoptotic signaling, and endothelial cell dysfunction. New therapeutic agents that can inhibit caspase activation may provide protection against infl...

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Detalles Bibliográficos
Autores principales:	Yu, Jinyan, Ma, Mengshi, Ma, Zhongsen, Fu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342375/ https://www.ncbi.nlm.nih.gov/pubmed/27419634 http://dx.doi.org/10.18632/oncotarget.10591

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