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Inhibition of primary breast tumor growth and metastasis using a neuropilin-1 transmembrane domain interfering peptide
The transmembrane domains (TMD) in membrane receptors play a key role in cell signaling. As previously shown by us a peptide targeting the TMD of neuropilin-1 (MTP-NRP1), blocks cell proliferation, cell migration and angiogenesis in vitro, and decreases glioblastoma growth in vivo. We now explored t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342376/ https://www.ncbi.nlm.nih.gov/pubmed/27351129 http://dx.doi.org/10.18632/oncotarget.10101 |