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Inhibition of primary breast tumor growth and metastasis using a neuropilin-1 transmembrane domain interfering peptide

The transmembrane domains (TMD) in membrane receptors play a key role in cell signaling. As previously shown by us a peptide targeting the TMD of neuropilin-1 (MTP-NRP1), blocks cell proliferation, cell migration and angiogenesis in vitro, and decreases glioblastoma growth in vivo. We now explored t...

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Detalles Bibliográficos
Autores principales: Arpel, Alexia, Gamper, Coralie, Spenlé, Caroline, Fernandez, Aurore, Jacob, Laurent, Baumlin, Nadège, Laquerriere, Patrice, Orend, Gertraud, Crémel, Gérard, Bagnard, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342376/
https://www.ncbi.nlm.nih.gov/pubmed/27351129
http://dx.doi.org/10.18632/oncotarget.10101