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Hypoxia-targeted (131)I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

Adoptively transferred mesenchymal stem cells (MSCs) home to solid tumors. Biologic features within the tumor environment can be used to selectively activate transgenes in engineered MSCs after tumor invasion. One of the characteristic features of solid tumors is hypoxia. We evaluated a hypoxia-base...

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Detalles Bibliográficos
Autores principales: Müller, Andrea M., Schmohl, Kathrin A., Knoop, Kerstin, Schug, Christina, Urnauer, Sarah, Hagenhoff, Anna, Clevert, Dirk-André, Ingrisch, Michael, Niess, Hanno, Carlsen, Janette, Zach, Christian, Wagner, Ernst, Bartenstein, Peter, Nelson, Peter J., Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342382/
https://www.ncbi.nlm.nih.gov/pubmed/27458162
http://dx.doi.org/10.18632/oncotarget.10758

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