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Hypoxia-targeted (131)I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery
Adoptively transferred mesenchymal stem cells (MSCs) home to solid tumors. Biologic features within the tumor environment can be used to selectively activate transgenes in engineered MSCs after tumor invasion. One of the characteristic features of solid tumors is hypoxia. We evaluated a hypoxia-base...
Autores principales: | Müller, Andrea M., Schmohl, Kathrin A., Knoop, Kerstin, Schug, Christina, Urnauer, Sarah, Hagenhoff, Anna, Clevert, Dirk-André, Ingrisch, Michael, Niess, Hanno, Carlsen, Janette, Zach, Christian, Wagner, Ernst, Bartenstein, Peter, Nelson, Peter J., Spitzweg, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342382/ https://www.ncbi.nlm.nih.gov/pubmed/27458162 http://dx.doi.org/10.18632/oncotarget.10758 |
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