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MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
Amplification of the MYCN oncogene, a member of the MYC family of transcriptional regulators, is one of the most powerful prognostic markers identified for poor outcome in neuroblastoma, the most common extracranial solid cancer in childhood. While MYCN has been established as a key driver of malign...
Autores principales: | Xue, Chengyuan, Yu, Denise M.T., Gherardi, Samuele, Koach, Jessica, Milazzo, Giorgio, Gamble, Laura, Liu, Bing, Valli, Emanuele, Russell, Amanda J., London, Wendy B., Liu, Tao, Cheung, Belamy B., Marshall, Glenn M., Perini, Giovanni, Haber, Michelle, Norris, Murray D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342392/ https://www.ncbi.nlm.nih.gov/pubmed/27448979 http://dx.doi.org/10.18632/oncotarget.10709 |
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