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Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma

Hepatitis B virus (HBV) X protein (HBx), a trans-regulator, is frequently expressed in truncated form without carboxyl-terminus in hepatocellular carcinoma (HCC), but its functional mechanisms are not fully defined. In this report, we investigated frequency of this natural HBx mutant in HCCs and its...

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Detalles Bibliográficos
Autores principales: Li, Weihua, Li, Man, Liao, Dongjiang, Lu, Xinpeng, Gu, Xia, Zhang, Qianqian, Zhang, Zhixiang, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342405/
https://www.ncbi.nlm.nih.gov/pubmed/27391153
http://dx.doi.org/10.18632/oncotarget.10399