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MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma

The phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) pathway is frequently hyper-activated upon vemurafenib treatment of melanoma. We have here investigated the relationship between SRY-box 10 (SOX10), forkhead box 3 (FOXD3) and microphthalmia-associated transcription factor (MITF) in the regul...

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Detalles Bibliográficos
Autores principales:	Alver, Tine N., Lavelle, Timothy J., Longva, Ane S., Øy, Geir F., Hovig, Eivind, Bøe, Sigurd L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342406/ https://www.ncbi.nlm.nih.gov/pubmed/27391157 http://dx.doi.org/10.18632/oncotarget.10422

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