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Sex-specific clinicopathological significance of novel (Frizzled-7) and established (MGMT, IDH1) biomarkers in glioblastoma

BACKGROUND: The Wnt receptor Frizzled-7 (FZD7) promotes tumor progression and can be currently targeted by monoclonal antibody therapy. Here, we determined the prognostic value of FZD7 for the overall survival of glioblastoma (GBM) patients, both as individual marker and taken in combination with th...

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Detalles Bibliográficos
Autores principales: Schiffgens, Salveena, Wilkens, Ludwig, Brandes, Alba A., Meier, Tatiana, Franceschi, Enrico, Ermani, Mario, Hartmann, Christian, Sandalcioglu, Ibrahim Erol, Dumitru, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342409/
https://www.ncbi.nlm.nih.gov/pubmed/27409829
http://dx.doi.org/10.18632/oncotarget.10465