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The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

The efficient treatment of hematological malignancies as Acute Myeloid Leukemia, myelofibrosis and Chronic Myeloid Leukemia, requires the elimination of cancer-initiating cells and the prevention of disease relapse through targeting pathways that stimulate generation and maintenance of these cells....

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Detalles Bibliográficos
Autores principales:	Giordani, Giorgia, Barraco, Marilena, Giangrande, Angela, Martinelli, Giovanni, Guadagnuolo, Viviana, Simonetti, Giorgia, Perini, Giovanni, Bernardoni, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342419/ https://www.ncbi.nlm.nih.gov/pubmed/27486815 http://dx.doi.org/10.18632/oncotarget.10879

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