MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment

Juvenile myelomonocytic leukemia (JMML) is an aggressive leukemia of early childhood characterized by aberrant proliferation of myelomonocytic cells and hypersensitivity to GM-CSF stimulation. Mutually exclusive mutations in the RAS/ERK pathway genes such as PTPN11, NRAS, KRAS, CBL, or NF1 are found...

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Detalles Bibliográficos
Autores principales: Leoncini, Pier Paolo, Bertaina, Alice, Papaioannou, Dimitrios, Flotho, Christian, Masetti, Riccardo, Bresolin, Silvia, Menna, Giuseppe, Santoro, Nicola, Zecca, Marco, Basso, Giuseppe, Nigita, Giovanni, Veneziano, Dario, Pagotto, Sara, D'Ovidio, Katia, Rota, Rossella, Dorrance, Adrienne, Croce, Carlo M., Niemeyer, Charlotte, Locatelli, Franco, Garzon, Ramiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342425/
https://www.ncbi.nlm.nih.gov/pubmed/27447965
http://dx.doi.org/10.18632/oncotarget.10577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342425/
https://www.ncbi.nlm.nih.gov/pubmed/27447965
http://dx.doi.org/10.18632/oncotarget.10577

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