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ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients

Several studies have evaluated the efficacy of neoadjuvant treatment using oxaliplatin and fluoropyrimidines in advanced gastric cancer (GC). However, preoperative biomarkers predictive of clinical outcome remain lacking. We examined polymorphisms in the MTHFR, DPYD, UMPS, ABCB1, ABCC2, GSTP1, ERCC1...

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Detalles Bibliográficos
Autores principales: Li, Ziyu, Xing, Xiaofang, Shan, Fei, Li, Shuangxi, Li, Zhongwu, Xiao, Aitang, Xing, Zhaodong, Xue, Kan, Li, Zhemin, Hu, Ying, Jia, Yongning, Miao, Rulin, Zhang, Lianhai, Bu, Zhaode, Wu, Aiwen, Ji, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342428/
https://www.ncbi.nlm.nih.gov/pubmed/27487151
http://dx.doi.org/10.18632/oncotarget.10961

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