Cargando…
Mutational load and mutational patterns in relation to age in head and neck cancer
Head and neck squamous cell carcinoma (HNSCC) is a cancer with well-defined tumor causes such as HPV infection, smoking and drinking.Using The Cancer Genome Atlas (TCGA) HNSCC cohort we systematically studied the mutational load as well as patterns related to patient age in HNSCC. To obtain a homoge...
Autores principales: | Meucci, Stefano, Keilholz, Ulrich, Tinhofer, Ingeborg, Ebner, Oliva A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342469/ https://www.ncbi.nlm.nih.gov/pubmed/27596625 http://dx.doi.org/10.18632/oncotarget.11312 |
Ejemplares similares
-
A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging
por: Schauer, Marianne, et al.
Publicado: (2015) -
Reprogramming of energy metabolism as a driver of aging
por: Feng, Zhaoyang, et al.
Publicado: (2016) -
PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status
por: Roodakker, Kenney R., et al.
Publicado: (2016) -
DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015) -
The rationale for including immune checkpoint inhibition into multimodal primary treatment concepts of head and neck cancer
por: Tinhofer, Ingeborg, et al.
Publicado: (2016)