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Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling

Ischemic preconditioning (IPC) maintains connexin43 (Cx43) phosphorylation and reduces chemical gap junction (GJ) coupling in cardiomyocytes to protect against ischemic damage. However, the signal transduction pathways underlying these effects are not fully understood. Here, we investigated whether...

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Detalles Bibliográficos
Autores principales: Rong, Bing, Xie, Fei, Sun, Tao, Hao, Li, Lin, Ming-Jie, Zhong, Jing-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342474/
https://www.ncbi.nlm.nih.gov/pubmed/27655723
http://dx.doi.org/10.18632/oncotarget.12087

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