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Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung

The neuregulin 1 (NRG1) fusion is a recently identified novel driver oncogene in invasive mucinous adenocarcinoma of the lung (IMA). After identification of a case of SLC3A2-NRG1 in a patient with IMA, we verified this fusion gene in a cohort of 59 patients with IMA. Targeted cancer panel sequencing...

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Detalles Bibliográficos
Autores principales: Shin, Dong Hoon, Lee, Donghoon, Wan Hong, Dong, Hyun Hong, Seung, Hwang, Jung-Ah, Il Lee, Byung, You, Hye Jin, Kook Lee, Geon, Kim, In-Hoo, Lee, Yeon-Su, Han, Ji-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342490/
https://www.ncbi.nlm.nih.gov/pubmed/27626312
http://dx.doi.org/10.18632/oncotarget.11913