Cargando…

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung

The neuregulin 1 (NRG1) fusion is a recently identified novel driver oncogene in invasive mucinous adenocarcinoma of the lung (IMA). After identification of a case of SLC3A2-NRG1 in a patient with IMA, we verified this fusion gene in a cohort of 59 patients with IMA. Targeted cancer panel sequencing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Dong Hoon, Lee, Donghoon, Wan Hong, Dong, Hyun Hong, Seung, Hwang, Jung-Ah, Il Lee, Byung, You, Hye Jin, Kook Lee, Geon, Kim, In-Hoo, Lee, Yeon-Su, Han, Ji-Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342490/ https://www.ncbi.nlm.nih.gov/pubmed/27626312 http://dx.doi.org/10.18632/oncotarget.11913

Ejemplares similares

NRG1 fusion in a French cohort of invasive mucinous lung adenocarcinoma
por: Duruisseaux, Michaël, et al.
Publicado: (2016)

Frequent NRG1 fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression
por: Trombetta, Domenico, et al.
Publicado: (2018)

NRG1 fusions in breast cancer
por: Howarth, Karen D., et al.
Publicado: (2021)

Clinicopathological Characteristics of NRG1 Fusion–Positive Solid Tumors in Korean Patients
por: Cha, Yoon Jin, et al.
Publicado: (2023)

Pathway-Based Analysis Using Genome-wide Association Data from a Korean Non-Small Cell Lung Cancer Study
por: Lee, Donghoon, et al.
Publicado: (2013)

Primary mucinous adenocarcinoma of the vulva, intestinal type
por: Lee, In Ho, et al.
Publicado: (2017)

Identification of Novel CDH1-NRG2α and F11R-NRG2α Fusions in NSCLC Plus Additional Novel NRG2α Fusions in Other Solid Tumors by Whole Transcriptome Sequencing
por: Ou, Sai-Hong Ignatius, et al.
Publicado: (2020)

CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization
por: Werr, Lisa, et al.
Publicado: (2022)

Two cases of mucinous adenocarcinoma of the stomach mistaken as submucosal tumor
por: Yu, Byung-Chul, et al.
Publicado: (2013)

Successful targeting of the NRG1 fusion reveals durable response to afatinib in lung adenocarcinoma: a case report
por: Wu, Xiaokang, et al.
Publicado: (2021)

A fusion of CD63–BCAR4 identified in lung adenocarcinoma promotes tumorigenicity and metastasis
por: Bae, Kieun, et al.
Publicado: (2020)

Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms
por: Lee, Yi-Ju, et al.
Publicado: (2016)

Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer
por: Choi, Yuri, et al.
Publicado: (2018)

Prognosis and Sensitivity of Adjuvant Chemotherapy in Mucinous Colorectal Adenocarcinoma without Distant Metastasis
por: Bong, Jun-Woo, et al.
Publicado: (2022)

Laparoscopic Treatment of Adult Sigmoidorectal Intussusception Caused by a Mucinous Adenocarcinoma of the Sigmoid Colon: A Case Report
por: Lee, Seok Youn, et al.
Publicado: (2011)

KRAS(G12) mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway
por: Liu, Yan, et al.
Publicado: (2016)

Optimizing palliative chemotherapy for advanced invasive mucinous adenocarcinoma of the lung
por: Jang, Yoon Jung, et al.
Publicado: (2021)

Durable response to afatinib in advanced lung adenocarcinoma harboring a novel NPTN-NRG1 fusion: a case report
por: Nie, Xin, et al.
Publicado: (2023)

Oncogenic Effect of the Novel Fusion Gene VAPA-Rab31 in Lung Adenocarcinoma
por: Yoon, Daseul, et al.
Publicado: (2019)

AVEN: a novel oncogenic biomarker with prognostic significance and implications of AVEN-associated immunophenotypes in lung adenocarcinoma
por: Fan, Dengxia, et al.
Publicado: (2023)

Effects of Lupenone, Lupeol, and Taraxerol Derived from Adenophora triphylla on the Gene Expression and Production of Airway MUC5AC Mucin
por: Yoon, Yong Pill, et al.
Publicado: (2015)

Systematic Analysis of Cellular Signaling Pathways and Therapeutic Targets for SLC45A3:ERG Fusion-Positive Prostate Cancer
por: Kim, Jongsu, et al.
Publicado: (2022)

Recurrence dynamics after curative surgery in patients with invasive mucinous adenocarcinoma of the lung
por: Yoon, Hyun Jung, et al.
Publicado: (2022)

Case of sclerosing pneumocytoma combined with a typical carcinoid and pulmonary adenocarcinoma in different lobes
por: Cho, Hwa Jin, et al.
Publicado: (2017)

Prognostic Comparison Between Mucinous and Nonmucinous Adenocarcinoma in Colorectal Cancer
por: Park, Jong Seob, et al.
Publicado: (2015)

Genomic characteristics of invasive mucinous adenocarcinoma of the lung with multiple pulmonary sites of involvement
por: Kim, Moonsik, et al.
Publicado: (2021)

A Patient with Duodenal Mucinous Adenocarcinoma Presenting as a Laterally Spreading Tumor
por: Chae, Myung Joon, et al.
Publicado: (2015)

Delayed Epidural Mucin Collection after Surgery for Spinal Metastatic Pancreatic Adenocarcinoma
por: Kim, Dong Ha, et al.
Publicado: (2017)

Effects of RET, NRG1 and NRG3 Polymorphisms in a Chinese Population with Hirschsprung Disease
por: Yang, Dehua, et al.
Publicado: (2017)

Primary Retroperitoneal Mucinous Cystadenoma
por: Lee, Seok Youn, et al.
Publicado: (2016)

Standardization of the pathologic diagnosis of appendiceal mucinous neoplasms
por: Kang, Dong-Wook, et al.
Publicado: (2021)

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival
por: Lee, Chung-Ta, et al.
Publicado: (2017)

Prognosis for Pneumonic-Type Invasive Mucinous Adenocarcinoma in a Single Lobe on CT: Is It Reasonable to Designate It as Clinical T3?
por: Kim, Wooil, et al.
Publicado: (2022)

Mucin1 and Mucin16: Therapeutic Targets for Cancer Therapy
por: Lee, Dong-Hee, et al.
Publicado: (2021)

Localization of Oncogenic Osteomalacia by Systemic Venous Sampling of Fibroblast Growth Factor 23
por: Lee, Ji-Yeon, et al.
Publicado: (2017)

Metachronous Intraductal Papillary Neoplasm of the Bile Duct and Intraductal Papillary Mucinous Neoplasm of the Pancreas in a Patient Diagnosed With Mucinous Adenocarcinoma
por: Brennan, Gregory T., et al.
Publicado: (2019)

Mucinous Adenocarcinoma of Colon
por: Zamir, Naima, et al.
Publicado: (2010)

Mucinous adenocarcinoma of the appendix
por: Feizi, Iraj, et al.
Publicado: (2015)

Epidemiology of Mucinous Adenocarcinomas
por: Benesch, Matthew G. K., et al.
Publicado: (2020)

Mucinous adenocarcinoma of the abdomen
por: Pan, Jiyong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kdi9t0uc7ihgijf1qjnl01pveq