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Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface

High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy and may arise in either the fallopian tube epithelium (FTE) or ovarian surface epithelium (OSE). A mutation in p53 is reported in 96% of HGSOC, most frequently at R273 and R248. The goal of this study was to identif...

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Detalles Bibliográficos
Autores principales: Karthikeyan, Subbulakshmi, Lantvit, Daniel D., Chae, Dam Hee, Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342521/
https://www.ncbi.nlm.nih.gov/pubmed/27563818
http://dx.doi.org/10.18632/oncotarget.11499

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