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Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface
High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy and may arise in either the fallopian tube epithelium (FTE) or ovarian surface epithelium (OSE). A mutation in p53 is reported in 96% of HGSOC, most frequently at R273 and R248. The goal of this study was to identif...
Autores principales: | Karthikeyan, Subbulakshmi, Lantvit, Daniel D., Chae, Dam Hee, Burdette, Joanna E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342521/ https://www.ncbi.nlm.nih.gov/pubmed/27563818 http://dx.doi.org/10.18632/oncotarget.11499 |
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