Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia

Chronic myeloid leukemia (CML) treatment with BCR-ABL inhibitors is often hampered by development of drug resistance. In a screen for novel chemotherapeutic drug candidates with genotoxic activity, we identified a bisindolylmaleimide derivative, IX, as a small molecule compound with therapeutic pote...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Jia, Deyong, Ao, Junping, Liu, Huijuan, Zang, Yi, Azam, Mohammad, Habib, Samy L., Li, Jia, Ruan, Xinsen, Jia, Hao, Wang, Xueying, Li, Baojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342526/
https://www.ncbi.nlm.nih.gov/pubmed/27564101
http://dx.doi.org/10.18632/oncotarget.11566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342526/
https://www.ncbi.nlm.nih.gov/pubmed/27564101
http://dx.doi.org/10.18632/oncotarget.11566

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