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Targeting Notch signaling as a novel therapy for retinoblastoma

Retinoblastoma is the most common intraocular malignancy of childhood. Notch plays a key role in retinal cells from which retinoblastomas arise, and we therefore studied the role of Notch signaling in promoting retinoblastoma proliferation. Moderate or strong nuclear expression of Hes1 was found in...

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Detalles Bibliográficos
Autores principales:	Asnaghi, Laura, Tripathy, Arushi, Yang, Qian, Kaur, Harpreet, Hanaford, Allison, Yu, Wayne, Eberhart, Charles G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342532/ https://www.ncbi.nlm.nih.gov/pubmed/27661116 http://dx.doi.org/10.18632/oncotarget.12142

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