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FRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases

FRMD6 is an Ezrin/Radixin/Moesin (ERM) family protein and a human homologue of Drosophila expanded (ex). Ex functions in parallel of Drosophila merlin at upstream of the Hippo signaling pathway that controls proliferation, apoptosis, tissue regeneration, and tumorigenesis. Even though the core kinas...

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Detalles Bibliográficos
Autores principales: Xu, Yin, Wang, Kaiqiang, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342536/
https://www.ncbi.nlm.nih.gov/pubmed/27661120
http://dx.doi.org/10.18632/oncotarget.12148