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Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo

Hepatocellular carcinoma (HCC) is a highly lethal malignancy mostly because of metastasis, recurrence and acquired resistance to conventional chemotherapy. Arsenic trioxide (ATO) is successfully used to treat hematological malignancies, and has been proven to trigger apoptosis in HCC cells. However,...

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Detalles Bibliográficos
Autores principales: Song, Jingjing, Zhao, Zhongwei, Fan, Xiaoxi, Chen, Minjiang, Cheng, Xingyao, Zhang, Dengke, Wu, Fazong, Ying, Xihui, Ji, Jiansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342569/
https://www.ncbi.nlm.nih.gov/pubmed/27655700
http://dx.doi.org/10.18632/oncotarget.12041