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Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells

Multiple myeloma (MM) is a malignant disorder of plasma cells characterized by active production and secretion of monoclonal immunoglobulins (IgG), thus rendering cells prone to endoplasmic reticulum (ER) stress. For this reason, MM cell survival requires to maintain ER homeostasis at basal levels....

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Detalles Bibliográficos
Autores principales: Catena, Valeria, Bruno, Tiziana, De Nicola, Francesca, Goeman, Frauke, Pallocca, Matteo, Iezzi, Simona, Sorino, Cristina, Cigliana, Giovanni, Floridi, Aristide, Blandino, Giovanni, Fanciulli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342573/
https://www.ncbi.nlm.nih.gov/pubmed/27655709
http://dx.doi.org/10.18632/oncotarget.12060