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The changing 50% inhibitory concentration (IC(50)) of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of density-dependent chemoresistance in ovarian cancer
Inconsistencies in the half-maximal (50%) inhibitory concentration (IC(50)) data for anticancer chemotherapeutic agents have yielded irreproducible experimental results and thus reciprocally contradictory theories in modern cancer research. The MTT assay is currently the most extensively used method...
Autores principales: | He, Yifeng, Zhu, Qiujing, Chen, Mo, Huang, Qihong, Wang, Wenjing, Li, Qing, Huang, Yuting, Di, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342590/ https://www.ncbi.nlm.nih.gov/pubmed/27683123 http://dx.doi.org/10.18632/oncotarget.12223 |
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