Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells

Amplification or overexpression of MYCN is involved in development and maintenance of multiple malignancies. A subset of these tumors originates from neural precursors, including the most aggressive forms of the childhood tumors, neuroblastoma and medulloblastoma. In order to model the spectrum of M...

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Detalles Bibliográficos
Autores principales: Fielitz, Kathrin, Althoff, Kristina, De Preter, Katleen, Nonnekens, Julie, Ohli, Jasmin, Elges, Sandra, Hartmann, Wolfgang, Klöppel, Günter, Knösel, Thomas, Schulte, Marc, Klein-Hitpass, Ludger, Beisser, Daniela, Reis, Henning, Eyking, Annette, Cario, Elke, Schulte, Johannes H., Schramm, Alexander, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342675/
https://www.ncbi.nlm.nih.gov/pubmed/27769070
http://dx.doi.org/10.18632/oncotarget.12766

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