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Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells
Selective targeting of the PML/RARα oncoprotein demonstrates a successful molecular targeted therapy in acute promyelocytic leukemia (APL) with a typical t(15:17) chromosomal translocation. The zinc-thiolate coordination is critical for structural stability of zinc finger proteins, including the PML...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342695/ https://www.ncbi.nlm.nih.gov/pubmed/27732960 http://dx.doi.org/10.18632/oncotarget.12531 |