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Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells

Selective targeting of the PML/RARα oncoprotein demonstrates a successful molecular targeted therapy in acute promyelocytic leukemia (APL) with a typical t(15:17) chromosomal translocation. The zinc-thiolate coordination is critical for structural stability of zinc finger proteins, including the PML...

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Detalles Bibliográficos
Autores principales:	Misra, Sougat, Selvam, Arun Kumar, Wallenberg, Marita, Ambati, Aditya, Matolcsy, András, Magalhaes, Isabelle, Lauter, Gilbert, Björnstedt, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342695/ https://www.ncbi.nlm.nih.gov/pubmed/27732960 http://dx.doi.org/10.18632/oncotarget.12531

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