Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions

Metabolic reprogramming is a feature of neoplasia and tumor growth. Sirtuin 1 (SIRT1) is a lysine deacetylase of multiple targets including metabolic regulators such as p53. SIRT1 regulates metaplasia in the pancreas. Nevertheless, it is unclear if SIRT1 affects the development of neoplastic lesions...

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Detalles Bibliográficos
Autores principales: Pinho, Andreia V., Mawson, Amanda, Gill, Anthony, Arshi, Mehreen, Warmerdam, Max, Giry-Laterriere, Marc, Eling, Nils, Lie, Triyana, Kuster, Evelyne, Camargo, Simone, Biankin, Andrew V., Wu, Jianmin, Rooman, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342700/
https://www.ncbi.nlm.nih.gov/pubmed/27494892
http://dx.doi.org/10.18632/oncotarget.11013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342700/
https://www.ncbi.nlm.nih.gov/pubmed/27494892
http://dx.doi.org/10.18632/oncotarget.11013

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